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NMN and NR together deliver a comprehensive approach to increase NAD+ levels. These NAD+ precursors work through complementary pathways - nicotinamide riboside employs NRK1 NRK2 enzymes while NMN skips certain enzymatic processes. This combination approach optimizes mitochondrial function and facilitates sirtuin activation. As NAD+ decline with age occurs, this dual approach counteracts multiple aspects of healthy aging.
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